Everything You Need to Know About Xeomin®
Xeomin injections help you achieve younger-looking skin by eliminating frown lines, smile lines, or hard wrinkles in just one simple appointment.
Written by Julie Davis, Founder Medically reviewed by Emily Arnold, PA-C Updated August 20, 2026 4 min read
If recent skincare trends have taught us anything, it’s that smoother, younger-looking skin is a never-ending quest. While keeping a consistent skincare routine can certainly help, many other factors can interfere with your aesthetic goals.
For those with forehead or frown lines, smile lines, or wrinkles, for instance, you can see more noticeable results through simple Xeomin injections. Offered by Pura Vida Medspa in Fleming Island, FL, Xeomin has become a popular method of relaxing the facial muscles to soften these lines. As a result, users look brighter and more relaxed.
What is Xeomin?
Xeomin is a prescription injectable used to soften dynamic wrinkles, meaning the lines that appear when your face moves. It treats creases in the forehead, around the eyes, and in between the eyebrows. Like BOTOX, it is approved by the Food and Drug Administration (FDA) and is safe for use in most adults, and it is one of the wrinkle relaxers patients across Jacksonville, FL ask us about most often.
The active ingredient is incobotulinumtoxinA, a form of botulinum toxin type A that is found in BOTOX as well. Once injected, it blocks the nerve signals behind muscle activity, temporarily reducing the targeted muscles’ ability to contract. With that movement quieted, the skin above stops folding and the lines it created gradually soften. The same ingredient treats medical conditions involving muscle stiffness and spasms, while aesthetic providers use it to smooth facial lines for a limited period.
Xeomin vs BOTOX - What’s the Difference?
Patients ask about this constantly, and the answer comes down to formulation. Xeomin is a “naked” or pure-form neurotoxin, meaning that it contains only a single active ingredient (botulinum toxin type A). BOTOX carries protective proteins around that active molecule and must be refrigerated.
That difference has a practical consequence. With no accompanying proteins for the immune system to respond to, patients have a lower chance of developing resistance (antibodies) that can limit how well the injectable works over years of treatment.
Facial movements such as frowning or squinting make your muscles contract, causing the skin to fold. As you age, the skin loses some elasticity, which means those frown lines become more persistent and long-lasting.
We offer Xeomin as a cosmetic wrinkle relaxing treatment for deep frown lines, crow’s feet, laugh lines, and similar concerns. A consultation with one of our friendly and experienced injectors will help determine the best course of treatment to meet your aesthetic goals. Read on to learn more about what to expect from your consultation and Xeomin injection below.
What to Expect with a Xeomin Injection
An appointment to receive a Xeomin injection takes less than 30 minutes and is performed in a private treatment room after your consultation. Most patients describe the discomfort as brief and mild, closer to a pinch than a pain, so you do not need local anesthesia unless it is requested.
Following your injection of Xeomin, you can generally return to your day as usual, but more intense activities such as running or working out should be avoided until the next day. Some possible side effects include redness, bruising, and swelling. These are common, short-lived, and can be concealed with makeup products. If you experience any concerning symptoms that do not go away after time, such as headaches, neck pain, or muscle weakness, please reach out to our office as soon as possible.
While the final results may vary, you will generally notice the improvements in your face about 3 – 4 days after the initial injection. Once Xeomin takes effect, you will see the difference for up to 3 months afterward. From there, we can help you schedule touch-ups and follow-up appointments as needed.
How to Know if Xeomin is Right For You
Patients with dynamic facial wrinkles such as crow’s feet, worry lines, and deep lines across the forehead should consider Xeomin as an injectable option. Discuss the possibility of using Xeomin with our skilled staff. As experts in facial anatomy, we know how to treat moderate to severe wrinkles and frown lines, so the result is both attractive and natural-looking. We can also address your questions and concerns about Xeomin and other neurotoxin treatments such as BOTOX, along with weighing the benefits and risks. If the lines you want softened sit still when your face does, the cause is more likely lost volume than muscle movement, and your provider will point you toward dermal fillers rather than a relaxer.
During your consultation, we will examine your medical history to ensure that Xeomin is safe and effective for you. Please disclose any allergies, current prescription medications, vitamins, and supplements to your injector. If you have received a botulinum toxin product in the last several months, or if you have a medical condition that affects the nerves and muscles, you may not be a candidate at this time. Pregnant or nursing mothers may also need to find an alternative treatment option to Xeomin.
Set Up Your Xeomin Consultation
You may have developed a strict skincare regimen by following advice from experts using top beauty products. When it comes to anti-aging, however, our professionals know that prevention is the best way to achieve a wrinkle-free future.
Whether you are looking for spa services, massages, or injectables, our team has you covered. Patients across Fleming Island and the greater Jacksonville area can turn to our experts to learn more information about Xeomin and other effective skincare treatments to combat the signs of aging. Our facility offers holistic care to heal and relax both the body and mind, so reach out to our friendly office overlooking the Eagle Harbor pond today.
Frequently Asked Questions
Xeomin Questions, Answered
Is Xeomin the same as Botox?
They belong to the same family and treat the same dynamic lines, but they are not identical products. Both use botulinum toxin type A. Xeomin is formulated without the accompanying proteins BOTOX carries, which is why it is often described as a naked or pure-form neurotoxin and why it does not need refrigeration. In practice the two feel very similar to receive. Your provider picks between them based on your muscle strength, your treatment history, and how you have responded to a neurotoxin before, not on what happens to be on the shelf.
How long does Xeomin take to work, and how long does it last?
Most patients start noticing the change about three to four days after their appointment, with the full effect settling in over the following week. From there, results generally hold for around three months before muscle movement gradually returns and the treated lines begin to reappear. That return is the cue to book a touch-up. Patients who treat consistently often find the interval stretches a little over time.
Can I switch from Botox to Xeomin?
Yes, and patients do it fairly often. A small number of people develop antibodies to the accompanying proteins in other neurotoxins over years of treatment, which can blunt the result, and the pure-form makeup of Xeomin is one reason a provider might suggest the switch. Bring your treatment history to your consultation, including roughly when you were last injected and how long your results have been lasting, because that history is what makes the recommendation useful.
How much does Xeomin cost at Pura Vida?
Neurotoxins are priced per unit rather than as a flat fee, so your cost depends on which areas you are treating and how many units your muscles actually need. That number is confirmed at your consultation once your provider has read your face, and there is no honest way to quote it before then. If you plan to maintain your results year-round, ask about membership options at your visit.
Who should not get Xeomin?
Xeomin is not the right choice if you are pregnant or nursing, if you have a medical condition affecting your nerves or muscles, or if you have a known sensitivity to botulinum toxin products. Recent treatment with another neurotoxin may also mean waiting before your next appointment. Disclose your allergies, prescriptions, vitamins, and supplements to your injector so this gets sorted before anything is placed rather than after.
All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.
Authored & Medically Reviewed
Written by
Pura Vida's founder, with two decades of healthcare leadership and a master's in health administration — built on relentless education and rigorous technology vetting.
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Medically reviewed by
Physician Assistant-Certified
A board-certified physician assistant specializing in aesthetic medicine, with a Master of Physician Assistant Studies from Augusta University.
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